What does ST-segment elevation in leads V2 and V3 of ≥ 0.2 mV indicate?

ST-segment elevation in leads V2 and V3 of ≥ 0.2 mV is a significant finding in an electrocardiogram (ECG) that indicates the presence of a ST-Elevation Myocardial Infarction (STEMI). This elevation suggests that there is an acute myocardial injury, typically caused by the occlusion of a coronary artery, leading to a lack of blood supply (ischemia) to the heart muscle.

In the context of STEMI, this specific elevation in leads V2 and V3 points to the involvement of the anterior wall of the heart, which is supplied by the left anterior descending artery. These findings often necessitate immediate medical intervention, such as angioplasty or thrombolysis, to restore blood flow and minimize myocardial damage.

Other conditions mentioned, such as stable angina, pneumothorax, and aortic dissection, do not typically present with this specific pattern of ST-segment elevation. Stable angina is characterized by chest pain that occurs with exertion but is relieved by rest, and it does not cause persistent ST-segment elevation. Pneumothorax may cause changes in the heart's positioning in the thoracic cavity but does not typically cause ST-segment elevation